Fenugreek is a plant that's used as a seasoning in the Middle East, Egypt, and India, but is it a good treatment for diabetes and high cholesterol? It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. When ingested in culinary quantities, fenugreek is usually devoid of adverse reactions. HbA1c was also significantly reduced compared with controls (P = 0.009); however, fasting serum insulin levels were not significantly different. Though it is mostly used for culinary purposes, there are also number of medicinal and beauty benefits of fenugreek powder. The Hindi name in English script is Methi, there are 2 types of fenugreek the seeds and the plant which can be cooked and used like spinach, I buy it dried here in Toronto Canada, I like it fresh but it has small oval leaves and you have to pick them off the stems. 11. In the botany, fenugreek is a small annual leguminous herb belonging in the Fabaceae family, genus: Trigonella. B., Yancey, A. M., Barnes, K. N., and Myles, T. D. The use of galactogogues in the breastfeeding mother. Monitor therapy.61, 62, 63, 78, Fenugreek is generally recognized as safe for use both as a spice and as a fiber. Available for Android and iOS devices. Home. Avoid use in pregnancy. In Persian it is Shanbalîleh, and in Arabic its name is Hilbeh. Fenugreek actually prevents the aggregation of platelets together, which is the mechanism by which one of the most common blood thinners, aspirin, works as well. Consider therapy modification.56, 57, 58, 59, Thrombolytic agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of thrombolytic agents. Studies have included T lymphoma cells, squamous cell, breast, pancreatic, and prostate cancer, among others.24, 25, 26, 27, 28, 29, 75. Standardization of seed content has been reported on.4, 5, 6, 7, 8. Fenugreek is a plant also known as Alholva, Bird's Foot, Bockshornklee, Bockshornsame, Chandrika, Fenogreco, Foenugraeci Semen, Greek Clover, Greek Hay, Greek Hay Seed, Hu Lu Ba, Medhika, Methi, Sénégrain, Trigonella, Woo Lu Bar, and other names. The seeds exhibit pungent aromatic properties 48); fenugreek is used as a spice in curry preparations 49), to flavour food, and to stimulate appetite.It has been observed that chronic oral administration of an ethanol extract of fenugreek (10 mg/day per 300 g body weight) increases food intake in rats, possibly due to the aromatic properties of the seeds 50). Each pod contains about 10 to 20 small, yellowish-brown, angular seeds, which are dried to form the commercial spice. it made sourcing for it more easy for me. Several coumarin compounds have been identified in fenugreek seeds, as well as a number of alkaloids (eg, trigonelline, gentianine, carpaine), including the alkaloid hydroxyisoleucine, which is considered to stimulate insulin secretion. Bleeding may occur. Outcome measures included the Unified Parkinson's Disease Rating Scale (UPDRS), and Hoehm and Yahr (H & Y) staging measured at baseline and at 6 months. The common name of any plant can differ region to region. Allergy to fenugreek is recognized, including severe responses such as asthma, anaphylaxis, and toxic epidermal necrosis. WebMD explores the medical benefits of this seed. Although no significant direct cytotoxic effects on the gastric cells or bactericidal effects on H. pylori were found, fenugreek was observed to have mild and moderate inhibitory activity on IL-8 at 50 and 100 mcg/mL, respectively, in H. pylori-infected gastric cells.85, Reduction in cataract incidence was demonstrated in diabetic rats receiving an extract of fenugreek seeds and leaves. The remaining residue is rich in nitrogen and potassium, and is used as an agricultural fertilizer.2, 3, The leaves contain at least 7 saponins, known as graecunins, which are glycosides of diosgenin. Studies in patients with type 2 diabetes and hypercholesterolemia have used from 1 g/day of a hydroalcoholic extract of fenugreek up to 100 g/day of germinated fenugreek seeds, whereas seed powder 1.8 to 2.7 g taken 3 times daily for the first 3 days of menstruation was used in primary dysmenorrhea (total daily dose, 5.4 to 8.1 g); 500 mg twice daily of a standardized extract was studied for management of postmenopausal symptoms. Fenugreek may lower blood glucose and cholesterol levels in people with diabetes. It is used both as an herb, from the leaves of the plant, and as spice, from the seeds. Diosgenin, a precursor used in commercial steroid synthesis, is extracted from the seeds. Along with the scientific name of Fenugreek, know the scientific names of other plants too. Still it is beneficial to know the common name of all garden plants. In another study, micturition and dizziness were reported within 24 hours of acute administration of a 40 mg/kg single dose of aqueous leaf extract.90 A trial evaluating the safety of a standardized hydroalcoholic extract of fenugreek seeds at a dosage of 300 mg twice daily over 6 months reported no hematological or biochemical effects, including effects on liver and kidney function tests, over placebo.33 In contrast, animal studies have repeatedly documented histopathological and hematological changes in the liver and kidney.90, Fenugreek should be used with caution in individuals taking thyroid hormones because animal studies suggest that it may alter T3 and T4 levels.66, 67, Allergy to fenugreek is recognized; asthma, rhinitis, sneezing, excessive tearing, bronchospasm, numbness of head, facial angioedema, wheezing, and toxic epidermal necrolysis have been documented in several case reports. As an herbal remedy, this is one of the most common uses and if true, it might be related to the seeds’ effect on estrogen and prolactin levels. The seeds also contain the saponin fenugrin B. Fenugreek also known as Methi in Hindi, has its botanical name as Trigonella Foenum-Graecum. In all 10 studies, significant effects were observed on fasting blood glucose (FBG) compared with controls (P < 0.001) in patients with diabetes (types 1 and 2) but not in participants without diabetes; doses less than 5 g/day were unlikely to produce effects. Consider therapy modification.56, 57, 58, 59, Salicylates: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of salicylates. Trigonella foenum-graecum. Saponins are quite bitter and can be found in many common foods such as some beans. No adverse effects were reported or observed with fenugreek extract.87. There are no clinical data regarding the use of fenugreek as an antitumor agent. Sample sizes ranged from 5 to 69 and most trials included patients with type 2 diabetes. Consider therapy modification.56, 57, 58, 59, 78, Herbs (anticoagulant/antiplatelet properties): May enhance the adverse/toxic effect of other herbs (anticoagulant/antiplatelet properties). Of the 130 related cases of liver injury related to supplements, 65% were from non-bodybuilding supplements and occurred most often in Hispanic/Latinos compared to non-Hispanic whites and non-Hispanic blacks. No side effects were observed.84, High levels of polyphenolic flavonoids (more than 100 mg per 100 g) have been isolated from fenugreek seeds.17 These were associated with dose-dependent protection of erythrocytes from antioxidant damage in an in vitro study.18, Models of toxicity in laboratory studies (including cardio-, hepato-, nephro-, and neurotoxicity) have shown that fenugreek exerts antioxidant protective effects.19, 20, 21, 22, 23. Fenugreek can be used as a vegetable, as seeds, or as dried herbs. Common name of Fenugreek is the name which changes with change in the regions.

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